{"created":"2023-06-19T10:00:02.449251+00:00","id":1040,"links":{},"metadata":{"_buckets":{"deposit":"85590731-3145-4ecf-95f4-cb51f366b2b0"},"_deposit":{"created_by":11,"id":"1040","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"1040"},"status":"published"},"_oai":{"id":"oai:kiui.repo.nii.ac.jp:00001040","sets":["1:166:168"]},"author_link":["3730","3731"],"item_2_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"25","bibliographicPageStart":"15","bibliographic_titles":[{"bibliographic_title":"吉備国際大学社会福祉学部研究紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of Kibi International University School of Social Welfare","bibliographic_titleLang":"en"}]}]},"item_2_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Compared with that of other human pathogens such as bacteria and virus, the proposed replicative process of prions is very simple. It means misfolding of a single protein, the normal cellular prion protein (PrPc), into a disease-associated form called PrPSc. This is followed by PrPSc aggregation and fragmentation of aggregates, which may increase the number of replicative products. Although the correctness of this model has not yet been proved formally, much evidence indicates that pathogen-encoded DNA and RNA are not needed for prion replication. Despite the simplicity of the replicative process, the human phenotypic range of prion diseases is very variable and includes the sporadic, inherited, and acquired forms of Creutzfeldt-Jacob disease. In addition, prion diseases occur in a wide range of animals and can be propagated within and between animal species. This article reviews selected papers dealing with molecular and clinical aspects of human prion diseases.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_2_description_16":{"attribute_name":"アクセション番号","attribute_value_mlt":[{"subitem_description":"KJ00009354879","subitem_description_type":"Other"}]},"item_2_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN10585327","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_20":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13418912","subitem_source_identifier_type":"PISSN"}]},"item_2_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"吉備国際大学社会福祉学部精神保健福祉学科"}]},"item_2_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Mental Health and Welfare, School of Social Welfare, KIBI International University"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"庄盛, 敏廉","creatorNameLang":"ja"},{"creatorName":"ショウモリ, トシキヨ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3730","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SHOHMORI, Toshikiyo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3731","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-12-20"}],"displaytype":"detail","filename":"KJ00009354879.pdf","filesize":[{"value":"342.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00009354879.pdf","url":"https://kiui.repo.nii.ac.jp/record/1040/files/KJ00009354879.pdf"},"version_id":"4d8c5b52-ac11-4dc9-962e-43d7d7f671e9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"プリオン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"クロイツフェルト-ヤコブ病","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"狂牛病","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"痴呆","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"prion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Creutzfeldt-Jacob disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"BSE","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dementia","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ヒト・プリオン病研究の現況","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒト・プリオン病研究の現況","subitem_title_language":"ja"},{"subitem_title":"Human Prion Diseases","subitem_title_language":"en"}]},"item_type_id":"2","owner":"11","path":["168"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-12-20"},"publish_date":"2016-12-20","publish_status":"0","recid":"1040","relation_version_is_last":true,"title":["ヒト・プリオン病研究の現況"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2024-05-24T05:56:19.084700+00:00"}