{"created":"2023-06-19T09:59:39.631375+00:00","id":631,"links":{},"metadata":{"_buckets":{"deposit":"cebfc9b5-fbf3-4e21-ba8c-7e6706b38b88"},"_deposit":{"created_by":11,"id":"631","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"631"},"status":"published"},"_oai":{"id":"oai:kiui.repo.nii.ac.jp:00000631","sets":["1:113:115"]},"author_link":["2225","2226","2227","2228","2229","2230","2231","2232","2233","2234"],"item_2_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"96","bibliographicPageStart":"91","bibliographic_titles":[{"bibliographic_title":"吉備国際大学保健科学部研究紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of Kibi International University School of Health Science","bibliographic_titleLang":"en"}]}]},"item_2_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"NGF 存在下のPC12変異細胞に対し、2Hz から10Hz までの超低周波振動音刺激を、30分間、50dB の条件の下与えた結果、5～10Hz の超低周波振動音刺激は、神経突起の成長を大きく促した。そして、NGF 添加のみのコントロール群に対する、神経突起成長率は8Hz の刺激が最も高く、コントロール比で約4倍の神経突起成長を促した。p38MAP キナーゼの活性化は、PC 変異細胞のニューロンの分化において重要な役割を果たす。そこで、PC12変異細胞において神経突起成長を促す超低周波振動音刺激が、p38MAP キナーゼの活性効果によって生じるかどうかの実験を行った。その結果、2～10Hz の超低周波振動音刺激が、p38MAP キナーゼの活性化を高める効果が証明された。この結果は、超低周波振動音刺激の効果は、PC12変異細胞内で神経突起成長を促すp38MAP キナーゼ・シグナル伝達経路があることを示唆している。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_2_description_16":{"attribute_name":"アクセション番号","attribute_value_mlt":[{"subitem_description":"KJ00009354799","subitem_description_type":"Other"}]},"item_2_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11296968","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_20":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13418904","subitem_source_identifier_type":"PISSN"}]},"item_2_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"吉備国際大学保健科学部作業療法学科"},{"subitem_text_language":"ja","subitem_text_value":"九州保健福祉大学保健科学部作業療法学科"},{"subitem_text_language":"ja","subitem_text_value":"九州保健福祉大学保健科学部作業療法学科"},{"subitem_text_language":"ja","subitem_text_value":"吉備国際大学保健科学部理学療法学科"},{"subitem_text_language":"ja","subitem_text_value":"吉備国際大学保健科学部作業療法学科"}]},"item_2_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Occupational Therapy, School of Health Science, KIBI International University"},{"subitem_text_language":"en","subitem_text_value":"Department of Occupational Therapy, School of Health Science, Kyushu University of Health and Welfare"},{"subitem_text_language":"en","subitem_text_value":"Department of Occupational Therapy, School of Health Science, Kyushu University of Health and Welfare"},{"subitem_text_language":"en","subitem_text_value":"Department of Physical Therapy, School of Health Science, KIBI International University"},{"subitem_text_language":"en","subitem_text_value":"Department of Occupational Therapy, School of Health Science, KIBI International University"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小池, 好久","creatorNameLang":"ja"},{"creatorName":"コイケ, 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impaired","subitem_title_language":"en"}]},"item_type_id":"2","owner":"11","path":["115"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-12-20"},"publish_date":"2016-12-20","publish_status":"0","recid":"631","relation_version_is_last":true,"title":["神経成長因子非誘導PC12変異細胞に対する超低周波振動音刺激による神経突起の誘導"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2024-05-22T07:19:44.089046+00:00"}